Assisting Nature since the first years of its operation was distinguished for its consistently high success rates. The expertise, dedication and love of our scientists for human reproduction and our couples, place us internationally in the highest positions in birth rates. Success rates are expressed numerically as clinical pregnancies (fetuses with cardiac function) or as births, either per embryo transfer or per cycle (eg one stimulation – 2 embryo transfers)
In the latter case, the Cumulative Pregnancy Rate per oocyte retrieval, based on the total number of embryos produced (COMFFETI pregnancy rate *), is considered the most correct way of expressing the results. This can be implemented, as the survival of the embryos after cryopreservation (vitrification) is excellent. Additionally, in the modern era of assisted reproduction it is often that no fresh embryo transfer occurs and all embryos are frozen to be transferred in a subsequent cycle. In this case the endometrium will not be influenced by the hormones used for the ovarian stimulation. As a result, a woman can undergo two or even three embryo transfers without receiving medication until she achieves the desired result, but with clearly increased chances.
* COMFFETI: Combined Fresh and Frozen Embryo Transfer per Individual
** Chart values are presented in percentages (%)
The presentation of the results of IVF treatments with homologous (own) oocytes is based on the following parameters:
Our Clinic is one of the first in the world to adopt the new Freeze All strategy and along with continuous research proves that in specific patients, such as those who produce many oocytes or have elevated progesterone levels, the freezing of all embryos and the transfer of embryos to a subsequent cycle – and not during the stimulation cycle – increases the chances of conceiving and giving birth to live babies. As you will see in the next diagram, the application of Freeze All Blastocyst Strategy our clinic achieves a Cumulative Birth Rate of 57.4% in women under 40 with only ONE ovarian stimulation!
At Assisting Nature, the chances of pregnancy increase significantly in all transfers resulting from an egg donation cycle. The total rates of clinical pregnancies in this case reach 77%.
Preimplantation genetic testing of aneuploidy in embryonic cells allows us to detect abnormalities in the number of the embryo chromosomes. With this technique, or as it is otherwise called PGT-A, we have the ability to detect genetic abnormalities in the embryos. Therefore, we have the ability to transfer only the “healthy” embryos – thus reducing the risk of miscarriage or syndromes, such as Down, Turner or Klinefelter syndromes, but also to increase the chances of giving birth to a healthy child.
Pregnancy rate: the percentage of positive pregnancy tests per number of embryo transfers.
Clinical Pregnancy rate: a pregnancy that is confirmed by ultrasound detection of gestational sac or fetal heartbeat per number of embryo transfers.
Live Birth rate: the number of deliveries resulted in a live born neonate per number of embryo transfers.
Cumulative rates: success rates (pregnancy/ clinical pregnancy/ live birth rates) determined by a single oocyte retrieval event, until a positive result is achieved or until all the produced embryos are utilized.
Fresh embryotransfer: the transfer of embryos in the IVF/ ICSI cycle, without them first being cryopreserved.
FRET (Frozen embryotransfer): thawing and transferring embryos, in a treatment following the IVF/ICSI cycle.
PGT-A (Preimplantation Genetic Testing for aneuploidy): This technique requires the biopsy of the embryo (at blastocyst stage) in order to obtain a small number of cells that will be tested regarding the chromosome composition of the embryo.