The first step for an In Vitro Fertilization program is stimulation of the ovaries with medication. This is necessary for the development of many follicles and lasts about 12-14 days. The stimulation protocol is chosen based on each couple’s medical history (age, previous attempts, etc). Monitoring is done every 2-3 days with hormone determination & ultrasound examination for the appropriate dose of drugs. When most of the follicles reach 18-20 mm in diameter, the last injection is given, which will result in the final maturation of the oocytes and ovulation.