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microTESE/ Testicular Biopsy- TESE

With testicular biopsy (TESE or micro-TESE), we have the ability to collect mature or immature sperm from the seminiferous tubules. The classical testicular biopsy (TESE), which has access only to the testicular tissue, is the method that has been used all these years.

Microsurgical retrieval (micro-TESE), performed with a high-powered surgical microscope, is a revolution in the field of sperm retrieval for non-obstructive azoospermic men as it involves an in-depth exploration of the testicular tissue.

The main advantage of micro-TESE compared to classical testicular biopsy is that sperm is found in a high percentage, even in men who have undergone a classical biopsy and had not found any sperm.

Additional advantages of this method over the classical biopsy include:

  • Increasing the likelihood of finding sperm per biopsy.
  • Minimal reduction of testicular tissue.
  • Reduces the quantity of tissue obtained.
  • Facilitates the embryologist in finding sperm.
  • Reduces the risk of damage to intratesticular blood vessels.

Once the samples are collected, the search for sperm begins with an examination under the microscope. It may take up to five hours to search for sperm in the samples. This is a challenging and labor-intensive process but very thorough and significant. Once sperm is found, it can either be used for fertilization or frozen for future use. Freezing sperm from men with spermatogenesis issues can be difficult because these sperm are usually scarce and may not survive the freezing process. Therefore, the best chance of pregnancy is to use fresh sperm shortly before in vitro fertilization. Micro-TESE represents a significant advancement in male reproductive surgery.

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